Metabolic control mechanisms

Substrate Cycles Provide Metabolic Control Mechanisms... 

B. Chance, D. Garfinkel, J. Higgins, and B. Hess, Metabolic control mechanisms A solution for the equations representing interaction between glycolysis and respiration in ascites tumor cells. 

D. Garfinkel and B. Hess, Metabolic control mechanisms. VII. A detailed computer model of the glycolytic pathway in ascites cells. J. Biol. Chem. 239, 971-983 (1964). 

Chance, B. Garfinkel, D. Higgins, J. Hess, B. Metabolic control mechanisms. 

See also G Protein Families and Subunits, Signal Transduction Agonists and Antagonists, G proteins in vision. Figure 12.13, Metabolic Control Mechanisms (from Chapter 12)... 

Other High-Energy Nucleotides Adenylate Energy Charge Major Metabolic Control Mechanisms Control of Enzyme Levels Control of Enzyme Activity (Figure 12.10)... 

Frieden, C. in Developmental and Metabolic Control Mechanisms and Neoplasia, Williams and Wilkins, Baltimore, 1965, p. 392. 

Lardy, H. A. (1952). The role of phosphate in metabolic control mechanisms. Jlu Biidogy of Phosphorus, Wolterink, L. F. (Editor) Michigan State College Press, 131-147. 

R. L. Singhal, J. R. E. Valadares, and W. S. Schwark, Metabolic control mechanisms in mammalian systems. IX. Estrogen-like stimulation of uterine enzymes by o,p -, , -trichloro-2,2-bis(p-chlorophenyl)ethane, Biochem. Pharmacol. 19, 2145-2155 (1970). 

Assuming that all life is explicable in terms of matter and energy, it follows that metabolic control mechanisms also are explicable in... 

Failure of a metabolic control mechanism in a given tissue leads to impairment of the metabolic pathway, and may result in illness owing to accumulation of precursors or absence of an essential metabolite(s). 

The metabolic control mechanisms (which are part of the metabolic network) maintain the steady state of the metabolic network, thereby maintaining the constancy of the intracellular environment against internal and external perturbations, i.e., in a state of homeostasis. 

---