Mesoderm patterning tinman expression

Initial tinman expression occurs at cellular blastoderm in the prospective mesoderm and is confined to the trunk mesoderm where it is initally modulated in a peri-t)dic pair-rule pattern (Bodmer et ah, 1990 Azpiazu and Frasch. 1993). During invagination and dorsal migration of the mesoderm, the entire trunk mesoderm expresses tinman mRNA in a uniform pattern. However, shortly before the mesoderm reaches the dorsal border of the ectoderm, tinman expression decreases in the ventral portions and its levels increase in the dorsaimost cells of the mesoderm. Be-... 

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