Mesityl gold derivatives

The addition of water and methanol to terminal alkynes has also been studied by Laguna et al. by pentafluorophenyl and mesityl gold derivatives. Both acidic and non-acidic conditions led to high activity, even in the presence of as little as 0.5 mol% of catalyst. The use of pentafluorophenyl compounds allowed them to obtain additional spectroscopic information in the stoichiometric reaction of the complex [Au (C6F5)2C1]2 and phenylacetylene, which showed that gold(III) was the active species in the catalytic process. The reaction followed the Markovnikov rule, as shown in the proposed mechanism (Scheme 8.13), delivering the corresponding ketones or diacetal products [96]. 

FIGURE Al.l Simple separation of four small molecules for calculations of practical use. Separation of mesityl oxide [an EOF (neutral) marker], p-hydroxyphenylacetic acid, p-hydroxybenzoic acid, and benzoic acid [in borate buffer, pH 8.3 3-s pressure ( 0.5 psi) injection]. Analysis was carried out on a Beckman P/ACE System 2050. Separation conditions capillary, 50 /rm x 40 cm (effective length), 47 cm total length bare fused silica T, 28°C voltage, 25 kV buffer, 100 mM borate, pH 8.3 detection, 200 nm. Inset data derived from System Gold (vs7.1) data management software. 

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