Mercury Interdependencies

Potentiometric EDTA titrations are best carried out with a mercury pool electrode (Figure 5.6) or a gold amalgam electrode. When this electrode dips into a solution containing the analyte together with a small amount of added Hg-EDTA complex, three interdependent reactions occur. For example, at pH = 8 the half cell reaction (a) which determines the electrode potential is related to the solution equilibrium by (b) and (c). 

Several different biomarkers have been evaluated for assessing renal damage however, renal parameters are interdependent (Verschoor et al. 1988). Furthermore, these markers are not specific for mercury... 

The World Health Organization (WHO, 1993, 1996) has defined the -kinetic and -dynamic components of intrahuman variability as being equal contributors to, and collectively constituting the total of, human variability. In order to ensure a conservative approach, these two interdependent components were added to give a composite uncertainty factor of three (i.e., 1.5 + 1.5 = 3) to account for the full range of variability attributable to mercury in the Seychelles study. A modifying factor of 1.5 was also used to... 

Figure 19.1 Mercury content recycling interdependence. Source GRS.

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