Membranes hybridization kinetics

Moreover, the unique adsorption properties of GEC allowed the very sensitive electrochemical detection of DNA based on its intrinsic oxidation signal that was shown to be strongly dependent of the multi-site attachment of DNA and the proximity of G residues to GEC [100]. The thick layer of DNA adsorbed on GEC was more accessible for hybridization than those in nylon membranes obtained with genosensors based on nylon/GEC with a changeable membrane [99,101,102]. Allhough GEC has a rough surface, it is impermeable, while nylon is more porous and permeable. DNA assays made on an impermeable support are less complex from a theoretical standpoint [7] the kinetics of the interactions are not compUcated by the diffusion of solvent and solutes into and out of pores or by multiple interactions that can occur once the DNA has entered a pore. This explained the lower hybridization time, the low nonspecific adsorplion and the low quantity of DNA adsorbed onto GEC compared to nylon membranes. 

Kislik, V., Eyal, A. (2000). Aqueous hybrid liquid membrane process for metal separation. Part I. A model for transport kinetics and its experimental verification. J. Membr. Sci., 169, 119-32. 

The order of permeability coefficient for the four gases through these PI-POSS hybrid membranes was P (CO2) > P (O2) > P (N2) > P (CH4), which follows the same order as their kinetic diameter (A) CO2, 3.3 O2, 3.46 N2, 3.64 CH4, 3.8 [109]. Compared with the pure PI membranes, a significant increase in permeability coefficient values was observed for all of the PI-POSS hybrid membranes, whereas the selectivity was comparable for different gas pairs. The higher permeability coefficients for the hybrid membranes were attributed to the presence of bulky porous POSS cages... 

Figure 1.2 Exploitable features of membrane reactors, (a) Enhancing the conversion of a reversible reaction in a packed-bed inert membrane reactor, (b) Enhancing the conversion of a reversible reaction in a catalytic membrane reactor, (c) Preventing slip in a reaction requiring stoichiometric feeds, (d) Enhancing the rate of a multiphase reaction, (e) Energetic, thermodynamic, or kinetic coupling of two reactions run on opposite sides of a membrane, (f) Hybrid of fixed-bed reactor (PER) and selective inert membrane reactor (IMR-P) in series. 79...

Fang, Y., Cheng, Q., and Lu, X.-B. (1998). Kinetics of in vitro drug release from chitosan/gelatin hybrid membranes, /. Appl. Polym. Sci., 68 1751. 

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