Melanins, production Melanocyte-stimulating

The mechanism of iris pigmentation due to latanoprost is unknown. In an in vitro experiment using uveal melanocytes, the addition of latanoprost increased melanin content, melanin production, and tyrosinase activity (18). Alpha-methyl-para-tyrosine, an inhibitor of tyrosinase (the enzyme that transforms tyrosine to levodopa), completely prevented the latanoprost-induced stimulation of melanogenesis. 

It can be beneficial to protect the skin against the sun before certain peels. Effective sim protection should start 2 weeks before a medium or deep peel and even before a series of superficial peels to inhibit melanocyte activity and avoid excessive stimulation of melanin production before the peel. 

The skin responds to any lesion, burn or abrasion with an inflammatory reaction that may be accompanied by melanocyte stimulation and excessive melanin production. This reaction is generally considered to last for 3 months at the most. 

Human skin contains various amounts of a natural pigment, melanin, which absorbs radiation, especially in the UV-B range. Melanin is found in specialized cells called melanocytes. The production of melanin is stimulated by exposure to UV-B, although a delay occurs between exposure and melanin formation. The pigmentation is found... 

Bergapten (5-methoxypsoralen) is a photosensitizing furocoumarine found in bergamot oil. Nowadays, EU legislation prohibits more than 1 mg/kg in cosmetic products, but in the past it was used as a tanning accelerator, since it increased skin sensitivity to UV light and thus stimulated melanocytes to produce melanin however, it also intensified erythana formation and skin cancer (Ashwood-Smith et al, 1980 Autier et al, 1997). 

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