Medium effects on NMR chemical shifts

Medium Effects on NMR Chemical Shift Most MO calculations of nuclear shielding relate to the case of a molecule in a vacuum. For nuclei forming the molecular skeleton, such as 13C, and nuclei with small shielding ranges, such as H, this may not be an unreasonable approximation. This is particularly true if comparison of the theoretical results is to be made with the experimental data taken on a molecule dissolved in an inert solvent. 

The V NMR spectrum of [VO (S )-OCHMeEt (R)-salicylaldehyde(benzyl-mercaptothiocarbonylhydrazonate) ] shows two signals for the dia-stereomers. Medium effects on NMR chemical shifts have been calculated for ions such as [V0(02)2(0H2)]-, [(VO)io(p2-0)9(P3-0)3(C5H702)6]... 

---