Medicinal uses of naphthyridines

N-Heterocychc scaffolds such as indolo[2,l-ii]isoquinohnes, pyrrolo[2,l-a] isoquinolines, and indolo/pyrrolo[2,l [l,6]naphthyridines are abundant in natural products and biologically active scaffolds, semiconductors, and luminescent materials. Verma and coworkers have described a rapid high yield synthesis of medicinally important indolo-, pyrrolo[2,l [l,6]naph-thyridines, and isoquinolines 89 via a copper-catalyzed tandem approach (2014TL(55)4724). This microwave-assisted protocol uses hydroxymethyl... 

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