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MDR-associated protein

Abbreviations. MDR, multidrug resistance MRP, MDR-associated protein TM, transmembrane. [Pg.362]

Abbreviations. ABC, ATP binding cassette P-gp, P-glycoprotein MRPs, MDR-associated proteins BCRP, breast cancer resistance protein. [Pg.367]

Tumor cells may become resistant when genetic changes occur during cell proliferation. Resistant cancer cells with the mdr-1 gene may possess a membrane-associated protein, p-glycoprotein, that facilitates efflux of chemotherapy agents out of the cells. Numerous attempts at blocking this efflux pump have been unsuccessful. [Pg.1281]

Members of the ABC family, which are involved in the cellular export of drugs, comprise multidrug resistance (MDR) 1/P-glycoprotein, the multidrug resistance associated proteins (MRP), and breast cancer resistance protein (BCRP). [Pg.113]

See other pages where MDR-associated protein is mentioned: [Pg.275] [Pg.364] [Pg.364] [Pg.245] [Pg.169] [Pg.238] [Pg.6] [Pg.390] [Pg.158] [Pg.1835] [Pg.275] [Pg.364] [Pg.364] [Pg.245] [Pg.169] [Pg.238] [Pg.6] [Pg.390] [Pg.158] [Pg.1835] [Pg.96] [Pg.401] [Pg.606] [Pg.414] [Pg.39] [Pg.206] [Pg.265] [Pg.272] [Pg.54] [Pg.174] [Pg.116] [Pg.258] [Pg.552] [Pg.12] [Pg.49] [Pg.314] [Pg.487] [Pg.136] [Pg.382] [Pg.500] [Pg.2290] [Pg.144] [Pg.745] [Pg.220] [Pg.1773] [Pg.23] [Pg.122] [Pg.126] [Pg.228] [Pg.564] [Pg.601] [Pg.602] [Pg.606]

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MDR-protein

Protein , association

Proteins associated