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Maximum and minimum drug concentration at steady state

For an intravenous bolus, the maximum drug concentration occurs at f=0 after a dose at steady state, and the minimum drug concentration occurs at f=T (i.e. one dosing interval after the dose is given). [Pg.240]

At time t after a dose is given at steady state  [Pg.240]

Equations 11.45 and 11.46 clearly indicate that, at steady state, the difference between max- [Pg.241]

Multiple dosing extrovoscular routes of drug administration [Pg.243]

Upon completion of this chapter, you will have the ability to  [Pg.243]




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