Matteson asymmetric homologation using

The treatment of arylboronic acids and esters with alkaline hydrogen peroxide to produce the corresponding phenols was first reported more than 75 years ago [324]. The oxidation of alkyl- and alkenyl- boronic acid derivatives leads to alkanols [40] and alde-hydes/ketones, respectively [85, 257, 279, 316]. With a-chiral alkylboronates, the re-action proceeds by retention of configuration (Equation 53, Figure 1.32) [359, 121]. In fact, the oxidation of boronic acids and esters is a synthetically useful process, mainly in the preparation of chiral aliphatic alcohols via asymmetric hydroboration reactions [300, 302], or from Matteson homologation chemistry [322]. Paradoxically, the... 

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