Matrix noncovalent compounds

Molecular imprinting is a method for the synthesis of polymers with predeterminated selectivity for various compounds. This technique uses noncovalent prearrangement of functional monomers in the presence of the print molecules prior to the polymerization for the creation of highly specific binding sites. After polymerization the print molecules are washed out of the macroporous polymer matrix. The result is a polymer with recognition sites due to the shape of the print molecules. The proper arrangement of the functional groups in the polymer have the affinity for the print molecules. This fact leads to the restriction that the structure of the enantiomers, to be separated, must be very similar to these of the print molecules. 

J. M. Cotter, R. J. Matrix-assisted laser desorption/ ionization of noncovalently bound compounds. Anal. Chem. 1995, 67, 4462-4465. 

Similarly, the aspect ratio of the filler will have an effect on the sensitivity of the composite to various dispersion states. Thus, the effectiveness of comparisons made across studies can be compromised further if aspect ratio is not well characterized, even when the same filler type and polymer matrix are considered. This effect is compounded by the faa that high-aspect ratio fillers are typically more difficult to be dispersed effectively. Finally, correlations between dispersion and composite conductivity are ambiguous when covalently or noncovalently bonded chemical additives are used to enhance dispersion, but which may also inhibit electron transport. 

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