Mass scanning protocol

Table 42.4 Modified scanning protocol for mass casualty incidents for a four-detector-row scanner, adapted from (Korner et al. 2006) The collimation for the head CT was increased to 2.5 mm, the chest and abdomen scan were fused, and the current-time product for the chest and abdomen had to be lowered because of ti4>e cooling issues. There are no standard MPR or additional reformations in different kernels. After the acute setting has cleared, those reformations can be calculated...

Because multielement detection capability is probably the major reason why most laboratories invest in ICP-MS, it is important to understand the impact of measurement criteria on detection limits. We know that in a multielement analysis, the qua-drupole s RF-to-DC ratio is driven or scanned to mass regions, which represent the elements of interest. The electronics are allowed to settle and then sit or dwell on the peak and take measurements for a fixed period of time This is usually performed a number of times until the total integration time is fulfilled. For example, if a dwell time of 50 ms is selected for all masses and the total integration time is 1 s, then the quadrupole will carry out 20 complete sweeps per mass, per replicate. It will then repeat the same routine for as many replicates that have been built into the method. This is shown in a simplified manner in Figure 12.8, which displays the scanning protocol of a multielement scan of three different masses. 

Figure 8.3 Positive ion LD TOF mass spectrum of blood from a P. vivax infected human patient (only asexual parasites have been observed by microscopy estimated parasitemia approximately 72 parasites/pl). Protocol C is used for sample preparation estimated number of parasites deposited per well is approximately 90. A commercial TOF system is used laser wavelength 337 nm. All one hundred single laser shot spectra, obtained from hnear scanning of an individual well, are averaged (no data smoothing). The characteristic fingerprint ions of detected heme are denoted.

Protocol for Detection of Glutathione or Cyano Adducts Using Constant Neutral Loss Scanning of Triple Quadrupole Mass Spectrometer... 

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