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Marine macrolide antifungal activity

Many macrolides of marine origin have been reported to show other interesting biological properties, such as immunosuppressive [473,474], antifungal [323,475,476], anti-actin [477], and anti-inflammatory activity... [Pg.728]

The antifungal macrolide halichondramide (3), isolated by Kernan et al. from the Kwa-jalein sponge of the genus Halichondria, showed the most significant in vitro activity of the compounds tested. With 50% inhibitory concentration (IC50) values approaching those for compounds used clinically, this marine natural product is a potential lead for the development of alternative chemotherapy for the treatment of malaria. [Pg.239]

See other pages where Marine macrolide antifungal activity is mentioned: [Pg.242]    [Pg.208]    [Pg.172]    [Pg.477]    [Pg.71]    [Pg.77]    [Pg.239]    [Pg.139]    [Pg.361]    [Pg.6]    [Pg.242]    [Pg.672]    [Pg.361]    [Pg.98]   
See also in sourсe #XX -- [ Pg.19 , Pg.549 ]

See also in sourсe #XX -- [ Pg.19 , Pg.549 ]



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Activity antifungal

Antifungal macrolide

Macrolide

Macrolides antifungal activity

Marine macrolide

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