Object-relational mapping tools

The business layer (or domain layer) is the center of the system that does the real work. It implements all business logic and workflows. In J2EE, EJB can be used to implement the Business layer. However, you can also use Plain Old Java Object (POJO) with an object-relational mapping tool or direct JDBC API to do the job. 

But you get more. A map is a tool that relates objects to each other. These relations may be distances as they appear on a roadmap, it may be frequencies or densities on a web exploration map or it may be metabolism-emotion relationships in a brain map. Hence the pharmacophoric map can be used as a filter by matching the property vectors and a library of synthetic and/or virtual ligands, sorting out putative binders. 

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