MAOIs Propranolol

Drugs that affect nefazodone include general anesthetics, sibutramine, sumatriptan, buspirone, carbamazepine, and propranolol. Drugs that may be affected by nefazodone include alcohol, benzodiazepines, buspirone, carbamazepine, cisapride, digoxin, haloperidol, HMG-CoA reductase inhibitors, MAOIs, propranolol, St. John s wort, cyclosporine, and tacrolimus. 

P-adrenergic blockers Propranolol used with MAOis may cause severe hypertension and slight bradycardia. The combination should be monitored carefully, especially in the elderly. 

---