Mannopyranosides irradiation

Molecular interactions between D-glucolipids and multilayered vesicles were also demonstrated with partially polymerized diacetylene units. Red vesicles constructed by sonication and subsequent UV irradiation formed a red precipitate with Con A which was redissolved by methyl-D-mannopyranoside to regenerate a red solution . ... 

Phytohaemagglutinins.—pH-Acetyl]concanavalin A has been shown to bind to, and partially inhibit the enzymic activity of, proline 2-oxoglutaratedioxygenase. The products obtained when concanavalin A is labelled with 4-azidophenyl a-D-mannopyranoside under u.v.-irradiation have been separated by affinity chromatography on Sephadex G-lOO at pH 5. One of the products is a monovalent dimer at pH 5 and a divalent tetramer at pH 7, indicating that photo-affinity labelling did not alter the quaternary structure of concanavalin A, although the haemagglutinating activity of the derivatized lectin was reduced. 

Willner et al. attached a thienylfulgimide to concanavalin A, a protein that forms complexes with pyranoses such as a-D-mannopyranoside, to form 31. UV irradiation increased the association constant. Also, a thienylfulgide-modified a-chimotrypsin 32 was synthesized by Willner et al. The esterification rate was controllable by photoirradiation. 

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