Manganese lipoxygenase

Hamberg, M., C. Su, and E. Oliw, Manganese Lipoxygenase. Discovery of a his-Allylic Hydroperoxide as Product and Intermediate in a Lipoxygenase Reaction, /. Biol. Chem. 273 13080-13088 (1998). 

Oxidation, major degradation mechanism of carotenoids, can be accelerated by heat, light, unsaturated fatty acids, peroxides, iron, copper, manganese, and the presence of some enzymes, as lipoxygenases, phenoloxidases, and peroxidases [4,6,7]. 

A similar W-band study was performed on a new variant of lipoxygenase in which the iron is replaced by manganese (MnLO). Compared with X-band, the signal was considerably simplified at W-band and allowed estimates of the zero-field splitting parameter (D = 0.07-0.1 cm ) and E/D (0.13-0.23), which indicated that the coordination environment of MnLO is similar to that in iron lipoxygenase. ... 

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