Manganese defidency

We have not mentioned manganese (Mn2 ) before in this Chapter but its presence, or rather its absence, is crucial to successful dtric add production. Manganese defidency in A. ttiger causes ... 

Nitrogen is normally supplied as an ammonium compound in dtric add fermentations and suffidrait has to be supplied to enable the effect of manganese defidency (increased levels of ammonium in the metabolic pool) to occur. Remember that increased metabolic pool anunonium has the effect of releasing the allosteric controls exerted on phosphofructokinase. 

Animals which are manganese defident have malformed bones which are similar to those observed in osteoporosis. They also have problems with their tendons. 

Manganese is widely distributed in food, and defidency in humans is unlikely. 

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