Mammal Protein-Based Biocomposites

Many researchers try to exploit polymer composites manufacturing techniques in order to tailor/improve the performance of collagen as biomaterial. In 2001, Kikuchi et al, have succeeded in manufacturing implants of HAp/collagen with a self-organized nanostructure and composition similar to bone. These implants 

A similar composite based on the PCL/coUagen was also studied as substrate for skin tissue engineering. The results revealed that composite films of collagen/PCL composites are favorable substrates for the growth of fibroblasts and keratinocytes and provide adequate system for skin repair [40]. Multilayered polyelectrolyte films synthesized from hyaluronic acid, coUagen, and poly(ethyleneimine), were investigated for their in vitro response as chondrosarcoma cells proliferation with interestingly tunable antitumor properties [41] (Table 14.3). 

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