Major intrinsic protein channels

The major intrinsic protein (MIP) of the eye lens, once thought to play a primary role as a gap junction between cells of the eye lens, a biophysically characterized aqueous channel that formed arrays in the eye lens (Gorin et al., 1984), was brought back to the fold as AQP-0. Many of the AQPs in eukaryotes are regulated by phosphorylation, pH, osmolarity, or binding of other proteins or ligands (Anthony et al., 2000 Engel et al., 2000). 

Voltage-gated ion channel VIC superfamily Voltage-gated channel Ryanodine/IPs receptor Ca channel Major intrinsic protein family Aquaporins... 

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