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Madelung indole synthesis modifications

The modification of the Madelung indole synthesis achieved by introduction of an electron withdrawing group (EWG) at the benzylic carbon atom of the N-acylated-o-alkylanilines has been quite successful. Orlemans et al. reported that indoles were isolated in decent yields when the amides were treated with t-BuOK in THF for a period of 10 minutes at room temperature. ... [Pg.142]

Scheme 2 Clark Modification of the Madelung Indole Synthesis... Scheme 2 Clark Modification of the Madelung Indole Synthesis...
See other pages where Madelung indole synthesis modifications is mentioned: [Pg.270]    [Pg.156]    [Pg.147]   
See also in sourсe #XX -- [ Pg.147 , Pg.151 , Pg.153 ]



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