Macromolecules transdermal route delivery

Subcutaneous still remains the predictable and controllable route of delivery for peptides and macromolecules. However, there is need for greater convenience and lower cost for prolonged and repeated delivery. An example of refinement of subcutaneous delivery is MEDIPAD (Elan Pharmaceutical Technologies), which is a combination of patch concept and a sophisticated miniaturized pump operated by gas generation. It was described in the report on transdermal drug delivery. 

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