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Macrolides Clozapine

CLOZAPINE MACROLIDES- ERYTHROMYCIN t clozapine levels with risk of clozapine toxicity Clozapine is metabolized by CYPIA2, which is moderately inhibited by erythromycin. Erythromycin is a potent inhibitor of CYP3A4, which has a minor role in the metabolism of clozapine. This may lead to 1 clearance and therefore t levels of clozapine Cautious use advised... [Pg.254]

A2 Cimetidine, fluoroquinolones, grapefruit juice, macrolides, isoniazid, zileuton Acetaminophen, clozapine, haloperidol, theophylline, tricyclic antidepressants, (R)-warfarin... [Pg.35]

Clozapine Bupropion eyelophosphamide Paelitaxel NSAIDs Dielofenae PPls Lansoprazole Beta-blockers Anesthetics Enflurane Macrolide antibiotics... [Pg.535]

Carbamazepine levels are increased by CYP3A4 inhibitors (cimetidine, macrolides, diltiazem, fluoxetine, ketoconazole, verapamil, valproate) levels are decreased by CYP3A4 inducers (cisplatin, doxorubicin, felbamate, phenobarbital, phenytoin, primidone, rifampin, theophylline). Carbamazepine may increase levels of clomipramine, phenytoin, and primidone and lithium toxicity may decrease levels of phenytoin, warfarin, oral contraceptives, doxycycline, theophylline, haloperidol, alprazolam, clozapine, ethosuximide, and valproate may interfere with other anticonvulsants. [Pg.304]

See other pages where Macrolides Clozapine is mentioned: [Pg.600]    [Pg.76]    [Pg.114]    [Pg.308]    [Pg.76]    [Pg.114]    [Pg.170]    [Pg.308]    [Pg.76]    [Pg.170]    [Pg.330]   
See also in sourсe #XX -- [ Pg.747 ]



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Clozapine

Macrolide

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