Macrocyclic chemistry

Organic Synthesis Theory and Applications Progress in Heterocyclic Chemistry Progress in Macrocyclic Chemistry... 

Dietrich, B., Viout, P., Lehn, J.-M., Macrocyclic Chemistry, Wiley-VCH Weinheim, 1993. 

MI3 Y. Z. Voloshin, O. A. Varzatskii, A. S. Belov, A. Y. Lebedev, I. S. Makarov, N. Bubnov, XXX International Symposium on Macrocyclic Chemistry, Drezden, Germany, 2005, 232. 

Emphasis in the early years of macrocyclic chemistry was given to the synthesis of a large number of N4-donor cyclic systems but synthetic procedures were subsequently developed for obtaining larger-ring species incorporating more than four donors [such as (38) and (39)]. 

Resulting from the widespread interest in macrocyclic ligand chemistry, an impressive array of synthetic procedures for macrocyclic systems has been developed. In spite of this, the synthesis of a new ring system frequently turns out to be far from trivial. Indeed, synthetic macrocyclic chemistry is often very challenging and, as well as a thorough knowledge of any metal-ion chemistry involved, skill in the subtle art of organic synthesis is also a valuable asset for those involved in the preparation of new cyclic systems. 

Lamb, J. D., Izatt, R. M. Christensen, J. J. (1981). Stability Constants of Cation-Macrocycle Complexes and Their Effect on Facilitated-Transport Rates, Ch 2 in Progress in Macrocyclic Chemistry, Volume 2, ed. R. M. Izatt J. J. Christensen. Wiley-Interscience, New York. 

The azamacrocycle 1,4,7-triazacyclononane (tacn) and its tris(A -methyl) analog (Me3tacn) are popular ligands in macrocyclic chemistry. Complexes of both and M (M = Ru, Os) containing the tacn ligand are dealt with together in this section along with several dinuclear, M—M bonded species. 

Potvin, P. G. Lehn, J. M. In Synthesis of Macrocycles. The Design of Selective Complexing Agents, Izatt, R. M., Christensen, J. J., Eds. Progress in Macrocyclic Chemistry 3 John Wiley Sons New York, 1987, Chapter 4, pp. 167-239. 

B-79MI52200 D. N. Reinhoudt and F. DeJong in Progress in Macrocyclic Chemistry, ed. 

In addition to macrocyclic hosts discussed above, many other molecules capable of selective complexation have been synthesized. They belong to so-called macrocyclic chemistry [30] encompassing crown ethers discussed in this Chapter, cryptands 61-63 [21], spherands 70 [31], cyclic polyamines 71 [32], calixarenes 18 [5], and other cyclophane cages such as 72 [33] to name but a few. Hemicarcerand 5 [2b] discussed in Chapter 1 and Section 7.3 also belongs to this domain. Typical macrocyclic host molecules are presented in Chapter 7. 

Raznoshik, H. Maimon, E. Zilbermann, I. Cohen, H. Meyerstein, D. 26th International Symposium on Macrocyclic Chemistry. Fukuoka, Japan, 2001. 

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