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Mackinlaya macrosciadia

Deoxyvasicinone (33) C11H10N2O 110-ni Unaria sp. (112) Mackinlaya macrosciadia (F. Muell.) F. Muell. (Ill) Peganum harmala L. (107-109) P. nigellastrum (110) Adhatoda vasica Nees (152)... [Pg.132]

C12H12N2O 99 Mackinlaya macrosciadia (F. Muell.) F. Muell. M. subulata Philipson (120,121)... [Pg.133]

The alkaloid vasicine was first isolated from Adhatoda vasica in 1925 but the structure (996) was elucidated only after a great amount of work, culminating in two independent syntheses in 1935 (B-53MI21301). It was made subsequently by a simple route from 2-aminobenzaldehyde and 4-amino-2-hydroxybutyraldehyde (994) followed by dehydration of the tricyclic intermediate (995) (60TL(25)44>. Vasicine has bronchodilatory activity of a low order. Two related unnamed alkaloids (997) and (998) were obtained in 1965 from members of the Araliaceae family, viz. Mackinlaya subulata and M. macrosciadia both had been synthesized earlier (66AJC151). [Pg.148]

From Mackinlaya subulata and M. macrosciadia the tetrahydropyr-ido[2,l-6]quinazoline 202 and its 11-oxo derivative 203 were ob-tained. - - ... [Pg.321]

Fitzgerald, Johns et al. (67, 99) have isolated two alkaloids (61) and (62) from the leaves and stems of Mackinlaya subulata and M. macrosciadia. Both were readily identified by a combination of physical and chemical methods, and the structures were confirmed by direct comparison with synthetic samples. [Pg.183]

See other pages where Mackinlaya macrosciadia is mentioned: [Pg.320]    [Pg.22]    [Pg.116]    [Pg.133]    [Pg.223]    [Pg.320]    [Pg.22]    [Pg.116]    [Pg.133]    [Pg.223]    [Pg.176]    [Pg.179]    [Pg.176]    [Pg.176]    [Pg.225]    [Pg.596]    [Pg.176]   
See also in sourсe #XX -- [ Pg.183 , Pg.215 , Pg.216 ]



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