Lysozyme diffusion constant

Figure 12. (a) The specific heat of the systems lysozyme-water (squares), and DNA-water (triangles), (b) The local tetrahedral order parameter derivative. d2/dT, for lysozyme (squares) and DNA hydration water (triangles), (c) Diffusion constant of lysozyme (squares), and DNA (triangles) hydration water [40]. 

Relaxation experiments on the interaction of the saccharide with lysozyme were carried out by Chipman Schinunel (1968). Their results, at that early time in the history of the application of the temperature jump method, should serve as a warning. The fact that reciprocal relaxation times increase linearly with ligand concentration should not be taken as evidence that one is observing a simple second order process, unless the rate constant derived from the slope corresponds to diffusion control (k= > IO M s ). Chipman Schimmel deduced a rate constant two orders of magnitude below that expected for a diffusion controlled reaction (see section 7.4). The complexity of the system was subsequently exposed by Holler, Rupley Hess (1969) and Halford (1975) by carrying out experiments at higher... 

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