Lycoperdic acid

Lycoperdic acid (30), as well as its ring-opened compound H02C(CH2)2C(0H)-(C02H)CH2CH(NH3)C02, have been isolated from this common forest mushroom.31... 

NO2, 1,4-Cyclohexadiene-l-glycine, 40B, 1092 iNOg, Lycoperdic acid, 44B, 435 2N202f L-Prolyl-L-alanyl cyclodipeptide, 45B, 2N2O8S 1.5 H2O, L-Mimosine sulfate hydrate. 

Next, synthesis of lycoperdic acid (62) was examined as an application of the present method. Lycoperdic acid (62), a... 

Me0H-H20 at room temperature for 30 min, hydrolysis of the lactone ring and translactonization occurred. Without purification, exposure to HCO2H- 1N HCl (to remove the Boc group) followed by treatment with Dowex G-10 afforded lycoperdic acid (62) in 71% yield from 77. 

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