Lutidinic acid

Figure 35 Perspective view of the green (orthorhombic) form of [V0(lut)(H20)]-2H20 (H2lut = lutidinic acid). The V atom is six-coordinate in a distorted octahedral site which closely approximates C symmetry the remaining two water molecules (w) link the chelate molecules by hydrogen bonding. Some other intemuclear distances are...

With the hydrazides (135)-(137) from lutidinic acid, monomeric compounds were obtained432 by reaction (58). For all complexes, the IR spectra suggest that the ligands (135)-(137) are pentadentate. 

Silver(n) complexes, 839-850 amino adds, 846 aqua,844,850 biguanides, 849 2,2 -bipyridyl, 843 carboxylates, 844 cinchomeronic acid, 842 dipicolinic acid, 842 dithiocarbamates, 845 isodnchomcronic add, 842 isonicotinates, 840 lutidinic acid, 842 N-heterocyclic ligands, 839 nicotinates, 840 1,10-phenanthroline, 843 phthalocyanines, 848 picolinates, 840... 

A further synthesis of quinuclidine was devised by Clemo and Metcalfe (197), who decarboxylated 2,4-lutidinic acid (CLVIII), obtuned by oxidation of 2,4-lutidine, and reduced the resulting pyridine-4-carT boxylic acid (CLIX) with sodium and alcohol. Esterification of the product afforded ethyl piperidine-4-carboxylate (CLX), which was condensed with ethyl chloroacetate to give ethyl piperidine-l-acetate-4-carboxylate (CLXII). Dieekmann cyclization followed by decarboxylation yielded 3-ketoquinuclidine, which on reduction by the Wolff-Kishner or Clemmensen methods gave quinuclidine. 

Pyridine-2,4-dicarboxylic acid (lutidinic acid) (C-H O.N) 700M... 

Lutidinic acid 9339 Mestilbol 3526 acid, 2-ethoxyethyl ester 2404... 

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