Lupinus latifolius

The most toxic quinolizidine alkaloids are tetracyclic with a pyridone nucleus. One of these is anagyrine. One case mentions in anagyrine being passed to the human body via milk from goats foraging on Lupinus latifolius. The anagyrine caused severe bilateral deformities of the distal thoracic limbs in a baby boy. 

Meeker, J. E. and Kilgore, W. W. 1987. Identification and quantitation of the Alkaloids of Lupinus latifolius. Journal of Agriculture and Food Chemistry, 35 431 33. 

Lupinus latifolius Cytisus scoparius Swainsona canescens Castanospermum australe Hordeum vulgare... 

Meeker JE, Kilgore WW. Identification and quantitation of the alkaloids of Lupinus latifolius. J Agric Food Chem 1987 35 431-3. 

Lupinus sericeus contains (—)-7-hydroxy-/3-isosparteine and 10, 17-dioxo-/3-isosparteine, which are also sparteines tetracychc quinohzidine alkaloids with a quinohzidine nucleus. Moreover, other alkaloids from this group include epi-aphylline and aphylline, alkaloids from L. latifolius, and (—)-lindenianine, an alkaloid from Lupinus lindenianus and Lupinus verbasciformis . Nuttalline... 

L. and L. albus L., 17-oxolupanine has also been detected . Hydroxylupa-nine and their esters occur in Lupinus bicolor, Lupinus densiflorus, L. latifolius, Lupinus polycarpus, Lupinus ruber, Lupinus burke L. rotundiflorus, L. mon-tanus, L. exaltatus, L. mexicanus, L. madrensis and L. polyphyllus ... 

Anagyrine has a molecular weight of 244 and a melting point of 264 °C. It only takes a ( )-form This alkaloid occurs in L latifolius, Lupinus arboreus, Lupinus caudatus, L. densiflorus, L. sericeus, Lupinus argen-teus, Lupinus leucophyllus ". Anagyrine was found in neither bitter nor sweet L polyphyllus Lindl., which grows in Finland . ... 

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