Luck Leads to a Simple and Powerful Anticancer Drug

Cisplatin Luck Leads to a Simple and Powerful Anticancer Drug 

The stereochemistry of cisplatin and its trans-isomtr had been solved by Alfi-ed Werner (see chapter 1) in 1893. The traw-isomer, unlike cisplatin, is not active against tumors. Subsequent studies of the mechanism of the cisplatin activity by many groups demonstrated that it binds to DNA by 

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