Lucanthone hydrochloride

The two most active compounds in this series are 5-[4-(2-diethylaminoethyl-amino)-l-naphthylazo] uracil (XLa) and 5-(4-amino-l-naphthylazo)uracil (XLb), (ANU). In mice infected with the Puerto Rican strain of S. mansoni, compound (XLa) causes an 82—100 per cent reduction in live worms when administered in the diet at 167—489 mg/kg per day for 14 days [334], whereas ANU (XLb) causes a 73—100 per cent reduction at 221—804 mg/kg per day for the same period [335]. These compounds are reported to be more effective than either lucanthone hydrochloride [334, 336] or the tris-(p-aminophenyl)carbonium salts [334—337]. Substitution of the amino groups at other positions in the... 

Homidium Bromide, B.Vet.C. Imipramine Hydrochloride Lucanthone Hydrochloride, B.P. 

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