Lower confidence limit (LCL) A statistical procedure to estimate whether the true value is lower than the measured value. [Pg.1456]

BMDL5 5% lower confidence limit of the benchmark dose. [Pg.224]

The upper and lower confidence limits for the standard deviation are obtained by dividing (A — 1)U by two entries taken from Table 2.28. The estimate of variance at the 90% confidence limits is for use in the entries Xoo5 X095 (for 5% and 95%) with N degrees of freedom. [Pg.202]

The lower end of the confidence interval, the lower confidence limit, is then given by [Pg.39]

Benchmark Dose (BMD)—Usually defined as the lower confidence limit on the dose that produces a specified magnitude of changes in a specified adverse response. For example, a BMDio would be the dose at the 95% lower confidence limit on a 10% response, and the benchmark response (BMR) would be 10%. The BMD is determined by modeling the dose response curve in the region of the dose response relationship where biologically observable data are feasible. [Pg.241]

For the special case where no failures are allowed y = 0) the 100(1 — a)+o lower confidence limit on rehabiUty is given by [Pg.15]

Examp/e 8. There are 40 components placed on an accelerated 80-hlife test. A 75% lower confidence limit on the rehabUity is desired. To use equation 51, a value of F must be looked up. In this case, n = 40 and y = 37, and the required value is [Pg.14]

Slope b is close to zero and/or ires is large, which in effect means the horizontal will not intercept the lower confidence limit function, and [Pg.117]

CL is inserted in Eqs. (2.18) and (2.19), with k - oo, and using the + sign. The intercept of the horizontal with the lower confidence limit function of the regression line defines the limit of quantitation, jcloq, any value above which would be quoted as 2f(y ) t s [Pg.116]

Establishment of areas where the signal is never detected, always detected, and where results are ambiguous. The upper and lower confidence limits are defined by the probability of a type 1 error (dark shading), and the probability of a type 2 error (light shading). [Pg.96]

Here again the quantity is the (1 — /3) percentile of a chi square distribution with V degrees of freedom. If only a 100(1 — a)% lower confidence limit is desired, it can be calculated from [Pg.11]

The US-EPA has in its 1996 Proposed Guidelines for Carcinogen Risk Assessment (US-EPA 1996) adopted the dose descriptor LEDio (the 95% lower confidence limit on a dose associated with a 10% extra tumor risk) whereas in its 2005 Guidelines for Carcinogen Risk Assessment (US-EPA 2005), no defined incidence has been recommended (see Section 6.3.2). Within the EU chemical s regulation, the dose descriptor T25 has been proposed (see Section 6.3.3). In the newly proposed MOE approach, the JECFA and the EFSA have recommended the dose descriptor BMDLio (see Section 6.4). [Pg.304]

In summary, for any stated value of the population correlation (p) the z statistic is denoted as Z(p), and the corresponding correlation confidence limits can be determined. For our example, the Z statistic of 0.6366 corresponding to the lower correlation coefficient confidence limit is shown in the graphic below (Graphic 60-6a) as having a p value of 0.562575 this represents the lower confidence limit for the correlation coefficient for this example. [Pg.394]

An eye should also be kept on the absolute size of the standard deviation before and after a proposed elimination. If the elimination of a questionable point results in a standard deviation that is markedly smaller than what is common experience for the test at hand, the P-test cannot be used for confirmation, unless S2 is replaced by either the method obtained during the validation, or its lower confidence limit. [Pg.242]

Q. You hinted at a rather remarkable claim. When there are several distinct measurements of a phase equilibrium feative, you suggest you can pick out a faulty measurement by comparison with a CALPHAD calculation. But surely the precision of such a calculation is linked to the precision of the thermochemical measiu-ements which contribute the input. Shouldn t a curve calculated by CALPHAD actually show upper and lower confidence limits depending on your judgement of the reliability of the input measurements [Pg.302]

See also in sourсe #XX -- [ Pg.393 , Pg.394 ]

See also in sourсe #XX -- [ Pg.203 ]

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