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Lodination anilines

Lastly, a formal synthesis of almotriptan (5) has been published by the Bosch group in Spain using an intramolecular Heck approach (Scheme 23). lodination of aniline 58 with bis(pyridine)iodonium(I) tetrafluoroborate followed by reaction with trifluoroacetic anhydride (TFAA) gave the o-iodotrifluoroacetanilide 66. Alkylation of 66 with methyl 4-bromocrotonate afforded 67, which underwent palladium catalyzed... [Pg.179]

See other pages where Lodination anilines is mentioned: [Pg.280]    [Pg.280]    [Pg.704]    [Pg.804]    [Pg.989]    [Pg.191]    [Pg.318]    [Pg.408]    [Pg.568]    [Pg.736]    [Pg.737]    [Pg.232]    [Pg.510]   
See also in sourсe #XX -- [ Pg.60 , Pg.62 ]



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Lodination

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