Locus coeruleus, glucose utilization

Fig. 9. Glucose utilization in the locus coeruleus during hypotension induced by hemorrhage. Upper deoxyglucose autoradiogram prepared from a normotensive rat (mean arterial blood pressure 100 mm Hg). Optical density (and glucose utilization) in the locus coeruleus is similar to adjacent pontine areas. Lower deoxyglucose autoradiograms prepared from a hypotensive rat (mean arterial blood pressure 75 mm Hg). Optical density (and glucose utilization) in the locus coeruleus (LC) is markedly elevated relative to adjacent pontine areas.

Fig. 21. Autoradiograms prepared from coronal sections of the rat brain in the region of the locus coeruleus together with one section stained with cresyl violet with the position of the locus coeruleus (LC) indicated. Following phentolamine (0.85 mg/kg/min), yohimbine (0.25 mg/kg/min), and phenoxybenzamine (42 mg/kg), glucose utilization is elevated markedly from that of adjacent pontine areas. (From Savaki et al., 1982a.)...

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