Local structural changes

V De Filippis, C Sander, G Vriend. Pi edictmg local structural changes that result from point mutations. Protein Eng 7 1203-1208, 1994. 

It is apparent that introducing the inert gas does induce a local structural change in the water. At the same time lines are still observed in these solutions, characteristic of pure water. Recall again our claim that the temperatures of the kinks are largely unaffected by the presence of solute even in a moderately high concentration (of both electrolytes and nonelectrolytes.)... 

In summary, it may be that binding of calcium (or magnesium) to the Ca2+-Mg2+ sites controls and stabilizes the structure of troponin c,245,246 and that the binding of calcium to the calcium-specific sites causes more localized structural changes which serve to trigger muscle contraction. 

Local structural changes, such as surface side-chain rotations, occur on time scales34 of 1CP11 to 10 10 s and length scales of several angstroms. A typical example of this kind of motion is illustrated in Figure 2, which shows the... 

Das TK, Mazumdar S, Mitra S (1995) Heme CD as a probe for monitoring local structural changes in hemeproteins alkaline transition in hemeproteins. J Chem Sci 107 497-503... 

A recent study has focused on structural and electronic aspects of a bacteriochlorophyl derivative (methyl bacteriophorbide) in the crystal phase [45]. The calculations are in good agreement with experimental data and provide evidence of a local structural change upon electronic excitation. 

The structure, however, is not static but is subject to thermally driven fluctuations. The local structure changes continuously as a function of time due to orientational and translational molecular motions. The time scale of these motions may range from nanoseconds up to several hundred years. The structure of the amorphous state as well as its time-dependent fluctuations can be analysed by various scattering techniques, such as X-ray, neutron, electron and light scattering. 

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