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Liver alcohol dehydrogenase-catalyzed ethanal

The initial rates (v in juM/min) of liver alcohol dehydrogenase-catalyzed ethanal reduction are measured in the presence of pyrazole as an inhibitor at the constant concentration of NADH (0.02 M) and the constant concentration of ethanal (2.0 mM), respectively. Propose respective inhibition types and estimate their inhibition constants. [Pg.143]

Ethanol (acetaldehyde) is produced from ethanol in the liver. Ethanol is oxidized in this reaction, which is catalyzed by the liver enzyme alcohol dehydrogenase. The ethanal that is produced in this reaction is responsible for the symptoms of a hangover. [Pg.399]




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