Lithium morpholide

A few computational studies focus on the saturated analog of 4//-l,4-oxazine, i.e., morpholine [98JCS(P2)1223, 00JCS(P2)1619, 00TL5077]. These cover the structure of lithium morpholide, cycloaddition reactions, and molecular complexes with genistein. 

A synthetically useful regioselective 5-lithiation of 3-formylfuran can be achieved by first adding lithium morpholide to the aldehyde and then lithiation at C-5, resulting in 2-substituted 4-formyl-furans, following loss of the amine during work-up. ... 

Die analoge Reaktion von Thiocarbonsaure-amiden, z. B. Thiobenzoesaure-morpholid, mit Butyl-lithium und Reduktion des nicht isolierten Zwischenproduktes mit Lithium-alanat ergibt Amine z.B. 4-(1-Phenyl-pentyl)-morpholin ( 90%) und analog 4-[I-(4-Melhoxy-phenyl) -pentyl -morpholin (59%)1 ... 

S-(5-butyl-2,4,6-trioxo-hexahydropyrimidin-5-yl-ester)-diethylester XII/2, 659 -S-[l-(bzw. 2)-carboxy-ethylester] Lithium-Dinatrium-Salz XII/2, 589 -0-8-chinolylester-0,0-diethylester XII/2, 639 O-Chloracetyl- -bis-fdiethylamid XII/2, 819 O-Chloracetyl- -O-ethylester-morpholid XII/2,819 -S-(2-chlor-allylester)-chlorid-methylaniid Xll/2,... 

The simultaneous replacement of uridine by deoxythymidine and galactose by a number of deoxy sugars to give non-natural donor substrates has also been reported [50], Partially protected a-sugar-1-phosphates were coupled to morpholidate-activated deoxythymidine-5-phosphate and subsequently deprotected in the presence of lithium hydroxide to give the corresponding dTDP sugars (see Table 1). 

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