Lithium 3-lithiopropoxide acylation

Williams has reported that orr/io-lithiated anisole may be acylated with the A -methoxy-A/ -methylamide of 2-(benzyloxy)acetic acid (equation 13) in higher yield than previously demonstrated with organocad-mium reagents (90% versus 40%). The ketone (23) is an early intermediate in an approach to quinocar-cin. Acylation of lithium 3-lithiopropoxide, generated from the stannane, afforded a hydroxy ketone without racemization at the a-position (equation 14). ... 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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