Lithium 4,4 -di-f-butylbiphenylide

Related Reagents. Copper(I) lodide-Triethylphosphine-Lithium Naphthalenide Lithium 4,4 -Di-f-butylbiphenylide Lithium l-(Dimethylamino)naphthalenide Potassium Naphthalenide Sodium Anthracenide Sodium Naphthalenide Sodium Phenanthrenide. 

Lithio-l-methoxycyclopropane can be generated by reductive lithiation of 1-methoxy-l-phenylsulfanylcyclopropane with lithium 1-dimethylaminonaphthalenide (Method A)146,147 or lithium 4,4 -di-f< r/-butylbiphenylide (Method B)148 in tetrahydrofuran at — 78 °C. 1-Lithio-l-methoxycyclopropanc reacts with enones and enals to produce 1-methoxycyclo-propanemethanols, which rearrange to vinylcyclobutanones 1 using tetrafluoroboric acid in tetrahydrofuran (Method C) 146,147 or triflic anhydride in the presence of 2,6-di-f 77-butyl-4-methylpyridine in dichloromethane (Method D).148 The latter method avoids destruction of acid-sensitive products (Table 11). 

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