Liquid chromatography-mass spectrometry rubber

Schoenmakers et al. [72] analyzed two representative commercial rubbers by gas chromatography-mass spectrometry (GC-MS) and detected more than 100 different compounds. The rubbers, mixtures of isobutylene and isoprene, were analyzed after being cryogenically grinded and submitted to two different extraction procedures a Sohxlet extraction with a series of solvents and a static-headspace extraction, which entailed placing the sample in a 20-mL sealed vial in an oven at 110°C for 5,20, or 50 min. Although these are not the conditions to which pharmaceutical products are submitted, the results may give an idea of which compounds could be expected from these materials. Residual monomers, isobutylene in the dimeric or tetrameric form, and compounds derived from the scission of the polymeric chain were found in the extracts. Table 32 presents an overview of the nature of the compounds identified in the headspace and Soxhlet extracts of the polymers. While the liquid-phase extraction was able to extract less volatile compounds, the headspace technique was able to show the presence of compounds with low molecular mass... 

Over the last few years there have been major developments in ionisation systems for examining the composition of components separated or present in liquid media. When examining extractable or migrating components from rubber materials, it is important to remember that certain types of extractable components may either breakdown or react when being examined by gas chromatography mass spectrometry (GC-MS). Alternatively components may be too high in molecular weight terms or be too involatile to be detected. 

See also Activation Analysis Neutron Activation. Atomic Absorption Spectrometry Principles and Instrumentation. Atomic Emission Spectrometry Principles and Instrumentation. Chromatography Overview Principles. Gas Chromatography Pyrolysis Mass Spectrometry. Headspace Analysis Static Purge and Trap. Infrared Spectroscopy Near-Infrared Industrial Applications. Liquid Chromatography Normal Phase Reversed Phase Size-Exclusion. Microscopy Techniques Scanning Electron Microscopy. Polymers Natural Rubber Synthetic. Process Analysis Chromatography. Sample Dissolution for Elemental Analysis Dry... 

Overview Industrial Applications. Liquid Chromatography Size-Exclusion. Mass Spectrometry Matrix-Assisted Laser Desorption/lonization. Particle Size Analysis. Polymers Natural Rubber Polyurethanes. 

Recent work includes extraction studies of aqueous extractants from acrylate coatings and adhesives using liquid chromatography LC)-mass spectrometry MS)/LC-MS-MS detection methods [21], extractant studies on elastomeric materials using MS techniques [22], and studies on rubbers using LC-atmospheric pressure chemical ionisation MS [23]. 

---