Liposomes optical stability

Optical stability can be monitored by using electron microscopy, after negative staining for suspensions or after freeze fracturing process. This technique provides indications of the size, shape and number of lamellae of liposomes. 

Using optical microscopy and cryo-TEM, we have recently discovered block liposomes, which are liposomes consisting of connected, but distinctly shaped, nanoscale liposome blocks spheres or pears connected to tubes or rods [58, 96, 97]. The key to this discovery is the curvature stabilizing ability of our new, highly charged DL MVLBisG2 (see Sect. 4) [24],... 

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