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Liposome immunosorbent assay

Liposome conjugates may be used in various immunoassay procedures. The lipid vesicle can provide a multivalent surface to accommodate numerous antigen-antibody interactions and thus increase the sensitivity of an assay. At the same time, it can function as a vessel to carry encapsulated detection components needed for the assay system. This type of enzyme-linked immunosorbent assay (ELISA) is called a liposome immunosorbent assay or LISA. One method of using liposomes in an immunoassay is to modify the surface so that it can interact to form biotin-avidin or biotin-streptavidin complexes. The avidin-biotin interaction can be used to increase detectability or sensitivity in immunoassay tests (Chapter 23) (Savage et al., 1992). [Pg.883]

The use of liposomes instead of the more common enzyme-produced signal as seen in enzyme-linked immunosorbent assay (ELISA) has a number of advantages. [Pg.401]

See other pages where Liposome immunosorbent assay is mentioned: [Pg.255]    [Pg.2060]    [Pg.255]    [Pg.2060]    [Pg.292]    [Pg.274]    [Pg.155]    [Pg.242]    [Pg.265]    [Pg.228]    [Pg.2689]    [Pg.12]    [Pg.186]    [Pg.251]    [Pg.677]   


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Immunosorbent

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