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Lipid sterilization methods

Aseptic Lltration is necessary for parenteral formulations. Because both lipids and the structure of liposomes are unstable at high temperatures, conventional terminal steam sterilization is not suitable for liposome formulations. Thus, the membrane aseptic Lltration is the most reliable method for sterilizing liposome formulations. Since the possibility exists for the membrane being defective, it is advisable to test the integrity of the assembled unit by carrying out a bubble-point test. This test... [Pg.397]

See other pages where Lipid sterilization methods is mentioned: [Pg.1345]    [Pg.202]    [Pg.165]    [Pg.977]    [Pg.33]    [Pg.112]    [Pg.132]    [Pg.132]    [Pg.152]    [Pg.74]    [Pg.41]    [Pg.552]   
See also in sourсe #XX -- [ Pg.979 ]



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Sterilization methods

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