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Linkages to the hydroxyl groups of serine

Glycosidic Linkages to the Hydroxyl Groups of Serine and Threonine Residues... [Pg.235]

Direct proof for the existence of O-glycosidic linkages involving the hydroxyl groups of serine and threonine was provided simultaneously from three laboratories. Anderson et al. (39) reported partial losses of serine and threonine after treatment with 0.52V NaOH (or 0.452V KOH) at 4°C or room temperature for about 20 hours. Subsequent reduction with platinum showed formation of some alanine and < -aminobutyric acid. Harbon et al (40) treated ovine submaxillary glycoprotein at pH 12.8 for 45 minutes at 70 °C. The serine and threonine content decreased by 78 and 60%, respectively. Treatment of this product with 0.1M sulfite, (pH 9, 24 hours, room temperature) caused a conversion of the dehydroserine residues to cysteic acid, but had no action on the dehydrothreonine residues. This reaction has been further studied by Simpson et al. (41). [Pg.235]

See other pages where Linkages to the hydroxyl groups of serine is mentioned: [Pg.172]    [Pg.1753]    [Pg.185]    [Pg.172]    [Pg.1753]    [Pg.185]    [Pg.361]    [Pg.228]    [Pg.95]    [Pg.314]    [Pg.123]    [Pg.93]    [Pg.131]    [Pg.2]    [Pg.516]    [Pg.414]    [Pg.45]    [Pg.1222]    [Pg.262]    [Pg.387]    [Pg.146]    [Pg.284]    [Pg.291]    [Pg.176]    [Pg.160]    [Pg.181]    [Pg.409]    [Pg.209]    [Pg.156]    [Pg.592]    [Pg.181]    [Pg.88]    [Pg.240]    [Pg.176]    [Pg.455]    [Pg.14]    [Pg.20]    [Pg.171]    [Pg.250]    [Pg.325]    [Pg.274]    [Pg.357]    [Pg.267]    [Pg.440]    [Pg.163]    [Pg.486]    [Pg.3]    [Pg.75]    [Pg.186]   


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