Linearity tests spectrometry

Richter S, Goldberg SA, Mason PB, Traina AJ, Schwieters JB (2001) Linearity tests for secondary electron multipliers used in isotope ratio mass spectrometry. Inti J Mass Spectrom 206 105-127 Rihs S, Condomines M, Sigmarsson O (2000) U, Ra, and Ba incorporation dining precipitation of hydrothermal carbonates imphcations for Ra-Ba dating of impure travertines. Geochim Cosmochim Acta 64 661-671... 

DiCorcia, A., Casassa, F., Crescenzi, C., Marcomini, A., and Samperi, R., Investigation of the fate of linear alkyl benzenesulfonates and coproducts in a laboratory biodegradation test by using liquid chromatography/mass spectrometry. Environ. Sci. Technol, 33, 4112-4118, 1999. 

Figure 10 Absorbance linearity of Orleans Blue food dye solution (in 1 mm cuvettes). (Fleming P and O Dea J (1991) Stray radiant energy test method in spectrometry based on direct transmittance spectrometry. Analyst 6-. 195-198 reproduced by permission of The Royal Society of Chemistry.)...

A recent paper compares the performances of GC-MS in SIM mode to those of GC coupled to tandem mass spectrometry (GC-MS/MS), either using an ion-trap or a triple quadrupole (Kinani et al, 2006). The ion trap was not suitable for the PASs determination due to a high LOQ (up to 40 mg/kg), lack of linearity and high variability (up to 26% of standard deviation when re-injecting a standard at a concentration of 10 mg/kg). The statistical comparison of the GC-MS method (with a single column) with the triple quadrupole results shows, in the latter case, a lower risk of false positives and negatives. However, the authors conclude that none of the tested methods is fully satisfactory from this point of view. 

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