Linear muscarine

Neurones which respond to ACh showed either excitation (35.5%) or inhibition (22 %) and the two responses can be differentiated pharmacologically, the excitatory response being both nicotinic and muscarinic, whilst inhibition was entirely muscarinic (Bradley et al., 1966a). Furthermore, the size of both responses was dependent upon the current used to expel the ACh, and hence upon the amount released, since this has been shown to be linearly related to the current (Bradley and Candy, 1970). 

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