Line broadening filtration

The use of in-line filters between injectors and colunm can prevent the accumulation of particulate material on the inlet frit of an analytical column, and can avoid back-pressure problems. A second, and often overlooked, site for filter installation is between the column and the detector. Cartridge-type filtration-units that contain readily changed, 0.2-/i,m filters are commercially available, and they contribute insignificantly to peak broadening. These filters are essential for the prevention of clogged detectors when laboratory-packed columns are used. 

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