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Sugar-assisted ligation

Brik, A. and Wong, C.-H. (2007) Sugar-assisted ligation for the synthesis of glycopeptides. Chemistry - A European Journal, 13, 5670-5675. [Pg.33]

Recently, another cysteine-free ligation strategy has been reported for the synthesis of glycopeptides. The method, dubbed sugar assisted ligation (SAL), utilizes a peptide thioester and a glycopeptide in which the carbohydrate is derivatized with a thiol auxiliary at the C-2 acetamide [52,53]. The proposed mechanism of this ligation, depicted in Scheme 7, involves... [Pg.1803]

The first example of ligation via side-chain auxiliary, termed sugar-assisted ligation (SAL), was developed by Wong and coworkers in 2006 and involved the use of a glycopeptide whereby the reactive thiol auxiliary was appended to the C-2... [Pg.41]

Scheme 10 Glycopeptides originally employed in sugar-assisted ligation (SAL)... Scheme 10 Glycopeptides originally employed in sugar-assisted ligation (SAL)...
Brik A, Yang YY, Ficht S, Wong CH (2006) Sugar-assisted glycopeptide ligation. J Am Chem Soc 128 5626-5627... [Pg.83]

Yang Y-Y, Ficht S, Brik A, Wong C-H (2007) Sugar-assisted ligation in glycoprotein synthesis. J Am Chem Soc 129 7690-7701... [Pg.263]

See other pages where Sugar-assisted ligation is mentioned: [Pg.204]    [Pg.268]    [Pg.1795]    [Pg.1801]    [Pg.1803]    [Pg.72]    [Pg.85]    [Pg.273]    [Pg.42]    [Pg.43]    [Pg.49]    [Pg.83]    [Pg.83]    [Pg.84]    [Pg.247]    [Pg.248]    [Pg.263]    [Pg.263]    [Pg.263]    [Pg.263]    [Pg.106]    [Pg.118]    [Pg.75]    [Pg.83]   
See also in sourсe #XX -- [ Pg.1803 ]



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