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Ligand, ligands target-guided

Figure 11. Potent tyrosine kinase inhibitors discovered through Combinatorial Target-Guided Ligand Assembly. Figure 11. Potent tyrosine kinase inhibitors discovered through Combinatorial Target-Guided Ligand Assembly.
D. J. Maly, I. C. Choong, J. A. Ellman, Combinatorial Target-Guided Ligand Assembly. Identification of Potent, Sub-type Selective c-Src Inhibitors , Proc. Natl. Acad. Sci, USA, 2000, 97, 2419-2424. [Pg.78]

Maly, D.J., Choong, I.C., Ellman, J.A. Combinatorial target-guided ligand assembly identification of potent subtype-selective c-Src inhibitors. [Pg.318]

Figure 7.1 Schematic representation of target-guided synthesis to generate a ligand (guest) templated by a target biomolecule (host) using the lock and key descriptors of Emil Fischer. Figure 7.1 Schematic representation of target-guided synthesis to generate a ligand (guest) templated by a target biomolecule (host) using the lock and key descriptors of Emil Fischer.
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See also in sourсe #XX -- [ Pg.89 ]



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Ligand-target

Target-guided ligand assembly

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